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Bo Li

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#machine learning Preprint May 2026

CellScientist: From Execution Feedback to Auditable Model-Revision Trajectories for Cellular Perturbation Prediction

This work presents CellScientist, a protocol-constrained workflow that converts execution and validation feedback into auditable model-revision trajectories, and produces both a selected predictor and an inspectable record of its development.

Meng-Ran Li, Bo Li, Jia-Yi Wang et al. · 0 citations
#artificial intelligence Review Sep 2026

See, Measure, and Reason: Learning Visually Grounded Reasoning in Pathology

ASECT improves over its backbone on three external pathology benchmarks covering classification and question answering beyond cellular composition tasks, and improves over its backbone on three external pathology benchmarks covering classification and question answering beyond cellular composition tasks.

Cheng-Yang Zhang, Wen-Chuan Zhang, Bo Li et al. · 0 citations
#machine learning Preprint Aug 2026

PertMind: Eliciting Emergent Biological Reasoning in LLM via Reinforcement Learning on Cellular Perturbation Data

It is shown that cellular perturbation atlases can instead become reinforcement-learning environments, where measured gene responses provide computable rewards for biological reasoning, and introduces PertMind, which combines trusted-trajectory supervised initialization with gene-, pathway-, and format-level reinforcem...

Zhen-Chao Tang, Xiao-Gang Xu, Jia-Fei Wu et al. · 0 citations
#machine learning Preprint Sep 2026

Discover, Falsify, Revise: Auditing Input-Use Claims from Source Code to Predictive Contribution in Agent-Discovered Cell Models

AI virtual cells aim to predict cellular responses to specified interventions, yet held-out predictive performance alone does not establish use of the supplied perturbation information. This prediction-claim gap matters in agentic model discovery, where language-model agents generate and revise predictors using score-b...

Meng-Ran Li, Bo Li, Cheng-Yang Zhang et al. · 0 citations
Open access Aug 2026

Mul‐PheG2P: decoupled learning and prediction–space fusion enables robust and interpretable multi‐phenotype genomic prediction

Mul‐PheG2P outperforms existing methods across diverse crop datasets, and provides a multi‐scale interpretability chain: at the macro level, it quantifies phenotypic contributions via attention‐based weighting; at the micro level, Integrated Gradients reveal the genetic basis of predictions.

Jia-Hui Wang, Yong Zhang, Bo Li et al. · 0 citations
Review Jul 2026

Do Pathology Vision-Language Models Truly See Pathology?

Results show that current pathology VLMs still exhibit a substantial gap between answer-side performance and visual-semantic binding, and this work presents PathBind, a benchmark comprising 2,600 samples that undergoes task-specific automated filtering and expert review to reduce textual shortcuts and improve entity-re...

Cheng-Yang Zhang, Wen-Chuan Zhang, Bo Li et al. · 3 citations

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