Jul 2026
Targeting JOSD2 degrades β-catenin to suppress colorectal cancer metastasis by disrupting RAS/ERK/β-catenin axis.
Yue Liu, Shuyu Yang, Wen-Han Zhang et al.
· Acta Pharmacologica Sinica · 0 citations
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Review
Jul 2026
Targeted protein degradation: bridging chemical biology and clinical translation.
An overview of the developmental trajectory of the TPD field is provided and how diverse modalities can be leveraged to address intracellular, membrane-associated, and extracellular protein targets are discussed.
Yu-bo Zhang, Junwei Fu, Yue Liu et al.
· Acta Pharmacologica Sinica · 0 citations