Longitudinal EEG, Seizure, and Developmental Patterns in Children With CDKL5 Deficiency Disorder in the First 2 Years of Life.
BACKGROUND AND OBJECTIVES Although there is near-universal early-onset epileptic encephalopathy in cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD), it has been observed clinically that EEGs are initially only mildly abnormal and worsen in the first 2 years of life. This study aimed to identify specific...