Author

Boao Xia

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Open access Aug 2026

Cell-Based Sensor for Extracellular DNA

First-generation LUNAR constructs can detect both oligonucleotides and plasmid double-stranded DNA with nanomolar sensitivity in mammalian cells and future work will focus on improving sensitivity, fold-change, and multiplexing capabilities for sequence-specific DNA detection.

Boao Xia, Nicholas A. Kalogriopoulos, Ruoxin Wen et al. · bioRxiv · 0 citations