Author

Bo-Da Guo

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Review Open access Aug 2026

Microplastic-induced male reproductive toxicity: animal models, key design parameters, and mechanistic insights

Microplastics (MPs) are pervasive environmental contaminants detected across air, water, soil, and food chains. Their presence in human reproductive tissues has raised concern that MP exposure may contribute to the global decline in male reproductive health. This review summarizes recent progress in animal models used...

Qiu-Jian Feng, Zhuo-Zhi Gong, E. Colonnello et al. · Environmental Sciences Europ... · 0 citations

Review Open access Jul 2026

Multi-Mechanistic Androgen Receptor Suppression by Chinese Medicine: A Polypharmacology Strategy Against Castration-Resistant Prostate Cancer

Castration-resistant prostate cancer (CRPC) is lethal because of persistent androgen receptor (AR) signaling, even when patients undergo androgen deprivation therapy. Resistance can arise through intratumoral androgen synthesis, AR overexpression, mutations in the ligand-binding domain, constitutively active splice...

Peiyao Ren, Yuanyang Tian, Boda Guo et al. · Integrative Medicine in Neph... · 0 citations