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Author

Boru Peng

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Aug 2026

Captopril Enables the Inhibition of tRNA-Mediated Tau Aggregation

Using in vitro reconstitution and high-resolution imaging, tRNA is identified as a major inducer of tau aberrant aggregation and captopril effectively inhibits both general and tRNA-induced tau aggregation, positioning CAP as a potential therapeutic candidate.

Boru Peng, Quan Deng, Xiaohua Zhu et al. · 0 citations