Author

Bosen Cui

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Preprint Aug 2026

Power and sample size calculations for causal mediation analysis with a binary mediator in randomized trials

Mediation analyses are increasingly conducted in randomized trials, but a sample size adequate for the total treatment effect may leave the natural indirect effect (NIE) or natural direct effect (NDE) substantially underpowered. Randomization does not extend to the mediator, so precision depends on the conditional medi...

Bosen Cui, Yu-Hong Yang, Fan Yang · 0 citations

Preprint Aug 2026

Transporting Trial Evidence Under Posterior Drift and Possible Hidden Confounding

Randomized trials provide internally valid treatment-effect evidence, but trial participants may not represent the target population. In contrast, observational studies are often closer to the target population, but their treatment assignment may be affected by possible hidden confounding. We develop a robust posterior...

X. Mao, Bosen Cui, Yuhong Yang · 0 citations