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Author

Brandt D. Pence

2 papers indexed here

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Open access Jul 2026

Modulatory effects of S1QEL on OxLDL-induced metabolic alterations and inflammatory responses in human monocytes

Background Oxidized low-density lipoprotein (OxLDL) plays a key role in initiating monocyte activation, glycolytic reprogramming, and pro-inflammatory cytokine production—processes that contribute to aging and progression of age-related diseases such as atherosclerosis and steatohepatitis. Mitochondrial reactive oxygen...

Negin Mosalmanzadeh, R. Maurmann, K. Davis et al. · 0 citations
Open access Aug 2026

Mycoplasma gallisepticum uses itaconate-associated mitochondrial inhibition to suppress host immunometabolism

Many pathogens actively suppress early host immune responses to enhance their fitness. Mitochondria function as key regulators of immune activation, yet whether pathogens suppress host immunity by manipulating mitochondrial metabolism in vivo remains largely unknown. During an innate immune response, the metabolite ita...

Soren Z Coulson, Reihane Eric, Chidambaram Ramanathan et al. · 0 citations

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