Author

Brenda J. Andrews

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Open access Sep 2026

Exploring roles for essential proteins in yeast filamentous growth identifies the WASP homolog Las17 as a regulator of the Cdc42-dependent fMAPK pathway

A collection of conditional alleles of essential genes was generated in a yeast strain that undergoes filamentous growth, revealing unexpected phenotypic diversity in essential alleles across populations of individuals.

Atindra N. Pujari, Ankita Priyadarshini, Zhijian Li et al. · bioRxiv · 0 citations

Open access Jul 2026

Role of Pbr1, a putative oxidoreductase, in the ER quality control and folding of yeast Fks1 glucan synthase

It is shown that PBR1 operates at the endoplasmic reticulum to support the folding and stability of Fks1, enabling proper cell-wall assembly and reveals an ER quality-control mechanism that enables constrained membrane proteins to fold efficiently and perform essential cellular functions.

Keisuke Obara, Hiroki Okada, Guihong Tan et al. · Proceedings of the National... · 1 citation