Breteler N. A.

Diffusion kurtosis imaging (gen)omics unravels mechanisms of cerebral small vessel disease

Cerebral small vessel disease (cSVD) is a leading cause of stroke and dementia. Traditional MRI-markers of cSVD are mainly detectable in older adults, but diffusion MRI (dMRI) measures of white matter microstructure can capture changes predisposing to cSVD earlier in life. In this study, we conducted large genomics and...