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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Brian Shuch

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Jul 2026

Abstract A060: Targeting metabolic–DNA repair vulnerabilities in SDHB- and FH-deficient renal cell carcinoma with the novel alkylating agent KL-50

FH- and SDHB-mutant RCC is identified as a molecularly defined subset characterised by epigenetic MGMT silencing, which may confer selective vulnerability to KL-50, which has the potential to overcome resistance mechanisms that have historically constrained the clinical utility of TMZ in this disease context.

Suparna M. Basu, R. Sundaram, Brian Shuch et al. · 0 citations

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