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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Brian T. Chait

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2 papers indexed here

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Open access Aug 2026

Structural and biophysical characterization of Mycobacterium tuberculosis DciA reveals functional convergence in DnaB helicase recognition

In bacteria, DnaB replicative helicases are essential for unwinding genomic DNA to provide the single‐stranded templates required for replication. The recruitment of the hexameric DnaB helicase to the origin of replication is mediated by distinct mechanisms that rely on specialized factors known as helicase loaders. Th...

Daniele Mazzoletti, Andrea Garavaglia, Hayden Fisher et al. · 0 citations
Open access Sep 2026

Multivalent Anti-ACE2 Nanobodies Confer Broad Pan-Sarbecovirus Protection

A nanobody discovery pipeline incorporating competition-based yeast surface display assays is optimized to isolate single-chain variable heavy chain-only antibody domains (VHHs or nanobodies) that bind human ACE2 and inhibit SARS-CoV-2 entry, showcasing their potential as broadly acting receptor-targeted biologics agai...

A. Bakasis, Rachel Patejak, Peter C. Fridy et al. · 0 citations

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