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Author

Brice Durocher

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Open access Aug 2026

Secreted nuclease effector neutralization by active site mimicry in Bacillota

A multivalent Tde/Tdi neutralization mechanism where an initial high-affinity interface increases the local concentration of Tdi’s P(Φ)4GG motif, enabling it to displace the Tde active site through structural mimicry, which may aid in eliminating the toxic effector.

Romina Abbasian, Bishal Parajuli, Liping Yu et al. · 0 citations

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