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Author

Brittania Moodie

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Open access Jul 2026

Systematic functional genetic analysis of cell-substrate adhesion

This work defines the requirements for cell-substrate adhesion in cultured human cells using orthogonal, large-scale functional genetic approaches and identifies established and uncharacterized regulators of adhesion, including genes involved in mitosis, focal adhesions, actin regulation, and membrane trafficking.

Kaitlyn Manzer, Kuan-Chung Su, Matteo Di Bernardo et al. · 0 citations
Open access Aug 2026

Kinetochore diversification in Naegleria reveals plasticity in the kinetochore-microtubule interface

It is shown that Naegleria kinetochores associate with chromatin and spindle microtubules and that their number is consistent with one kinetochore per chromosome, consistent with a model in which the reliance on bulk charge complementarity rather than residue-specific interactions permits significant sequence divergenc...

Andrew S. Kennard, Emily M. Larkin, Jacob M. Ritz et al. · 0 citations

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