Associations of per- and polyfluoroalkyl substances (PFAS) exposures and firefighting experience with microRNA signatures previously linked to Amyotrophic Lateral Sclerosis (ALS): a cross-sectional analysis of active-duty municipal and airport firefighters.
Significant associations between PFAS exposure, firefighting status, and ALS-related miRNAs suggest that PFAS exposure and firefighting characteristics are associated with miRNA expression patterns previously linked to ALS, warranting further investigation into potential biological pathways.