Author

Bruno Kluwe-Schiavon

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Open access Sep 2026

Atlas-Guided Cell-Specific Transcriptomics Identifies Pathway-Level Remodeling of Human Hypothalamic CRH Neurons in Opioid Use Disorder

Opioid use disorder (OUD) disrupts hypothalamic stress signaling, yet the molecular state of human paraventricular nucleus (PVN) corticotropin-releasing hormone (CRH) neurons remains poorly defined. Using single-nucleus RNA sequencing of 343,819 human hypothalamic nuclei, we applied complementary human HYPOMAP/MapMyCel...

Lorna Barrall, Phillip Urbanczyk, Bruno Kluwe-Schiavon et al. · bioRxiv · 0 citations

Review Open access Sep 2026

The Role of Innate Lymphoid Cells in Autoimmune, Allergic and Infectious Diseases: A Systematic Review.

Innate lymphoid cells (ILCs) are tissue-resident immune cells that functionally mirror CD4+ T helper (Th)1, Th2 and Th17 cells, and are accordingly classified as ILC1, ILC2 and ILC3. Additional members of the ILC family include lymphoid tissue inducer (LTi) cells and natural killer (NK) cells. Abundant at barrier surfa...

L. F. Luckmann, H. R. Dal-Pizzol, Louise M. Lückmann et al. · Immunology · 0 citations