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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Bünyamin Akgül

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Open access Jul 2026

METTL3 promotes cell-cycle progression via activation of transcriptional elongation.

This work identifies the m6A methyltransferase METTL3 as a direct substrate of the mitotic kinase CDK1 in mammalian cells and reveals a mechanism by which transcriptional elongation is coordinated with chromosome segregation fidelity.

Azime Akçaöz-Alasar, Yanhua Wang, Hang Li et al. · 1 citation
Open access Jul 2026

METTL3 modulates cell viability and motility in HCC1143 and MDA-MB-231 triple-negative breast cancer cells

It is discovered that METTL3 depletion uniquely triggers a severe halt in cell division in HCC1143 cells, while universally disrupting actin-associated cell motility across different backgrounds, demonstrating that METTL3 acts as a context-dependent modulator of cell fate rather than a monolithic driver.

Buket Sağlam-Şen, Azime Akçaöz-Alasar, Ahmet Batuhan Dondurur et al. · 0 citations

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