Open access
Sep 2026
Oxygen-responsive bacterial glycosphingolipid links symbiont fitness and immune development in neonatal host
Summary Symbiotic gut bacteria must re-establish themselves in every host generation, yet the molecular strategies enabling this inheritance remain poorly understood. Here we show that Bacteroides fragilis uses a membrane glycolipid, alpha-galactosylceramide (BfaGC), to colonize the neonatal gut. Genome-wide fitness pr...
Kyoo Heo, Da-Jung Jung, Ji-Sun Yoo et al.
· Cell · 1 citation