Author

Byron W H Mui

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Open access Aug 2026

Generation of two induced pluripotent stem cell lines from Marfan syndrome patients carrying FBN1 mutations

Induced pluripotent stem cell lines derived from two Marfan syndrome patients with mutations in the FBN1 gene exhibited typical iPSC morphology, normal karyotype, undifferentiated states, and trilineage differentiation capacity.

Byron W H Mui, M. Chorsi, Christopher D. Yan et al. · Stem Cell Research · 1 citation

Review Open access Aug 2026

Clinical landscape of human pluripotent stem cell-derived cardiomyocyte therapy.

The pathophysiological rationale for cell-based therapy in heart failure with reduced ejection fraction is summarized, and the preclinical foundations of distinct hPSC-derived product formats are examined, including cell suspensions, epicardial sheets, engineered heart muscle, and cardiac spheroids, each with distinct...

Byron W H Mui, E. Neofytou, Joseph C. Wu · Cell Reports Medicine · 0 citations