Author

C. Abbineni

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Sep 2026

Discovery of cyanocarbonimidodithioates as novel non-hydroxamate zinc-binding groups for selective HDAC8 inhibition: Design, synthesis, biological evaluation, anticancer activity, and in silico studies.

Sai Chaitanya Kosana, Hrushikesh S. Chaudhari, Ashna Fathima et al. · Bioorganic chemistry (Print) · 0 citations

Open access Aug 2026

Exploration of non-hydroxamate based quinoline analogues as HDAC8 inhibitors

Novel non-hydroxamate-based quinoline analogues were designed and explored as HDAC8-selective inhibitors that exhibit nanomolar HDAC8 enzymatic inhibition and establish these compounds as promising HDAC8 modulators with potential for therapeutic development in neuroblastoma.

N. V. M. Rao Bandaru, Vandana Joshi, M. Schweipert et al. · RSC Advances · 0 citations