Open access
Aug 2026
In silico analysis of transcriptomic datasets reveals nonlinear gene expression trajectories in aging microglia and Alzheimer's disease.
It is suggested that middle age may represent a critical transition stage preceding neuroinflammation and neurodegeneration, making it an attractive window to identify preventive or therapeutic targets in early AD.
Andrés Muedano-Sosa, Magalli Trujillo-Pineda, Samuel Ruiz-Pérez et al.
· Experimental Gerontology · 0 citations