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Author

Cheryl H. Arrowsmith

2 papers indexed here

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Open access Sep 2026

Chemically induced USP21-KLHL12 association recruits USP21 to COPII assembly

Ubiquitin-specific protease 21 (USP21) is a deubiquitinase implicated in various biological processes and disease states, including cancer. To better understand USP21 protein interaction networks, we used biotin identification proximity labeling, and uncovered USP21 interactions with the cytoskeleton, endosomal, and tr...

Victoria Vu, Michael Kanaris, Esther Wolf et al. · 0 citations
Open access Jul 2026

Site-Specific Hydrogen–Deuterium Exchange Mass Spectrometry for Deep Explorations of Dynamic Shifts in Protein–Drug Interactions

This work demonstrates a sensitive, broadly applicable method for single amino acid resolution, i.e., site-specific HDX-MS measurements and explores the greatly enhanced analytical power that arises from site specificity, including binding mode characterization, affinity ranking, and the detection of features that are...

J. Anacleto, Esther Wolf, S. Ackloo et al. · 1 citation

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