Open access
Sep 2026
NRF2 signaling drives chemoresistance in NSCLC and glioblastoma.
Analysis of cellular responses in cell lines exhibiting distinct sensitivities to temozolomide and cisplatin indicates that the NRF2/GSH pathway plays a crucial role in TMZ and cisplatin resistance and that pharmacological GSH depletion enhances the sensitivity of NRF2-high, chemotherapy-resistant cells to these agents...
I. de Souza, L. K. Monteiro, Ana Beatriz da Silva Teixeira et al.
· Molecular and Cellular Bioch... · 0 citations