Author

C. Ballantyne

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Review Open access Sep 2026

Targeting Lipoprotein(a): A New Era in Cardiovascular Disease Prevention

Novel unapproved therapies, including an antisense oligonucleotide, small interfering RNAs, and an oral small molecule have demonstrated Lp(a) reductions of up to 99% and are being tested in ongoing cardiovascular outcomes trials to determine whether pharmacologic Lp(a) lowering translates into reduced cardiovascular e...

Yakubu Bene-Alhasan, V. Nambi, Layla A. Abushamat et al. · Methodist DeBakey Cardiovasc... · 0 citations

Open access Jul 2026

Comprehensive Evaluation of Atherosclerotic Cardiovascular Disease Risk Predictors Across the Pooled Cohort Equations, Predicting Risk of Cardiovascular Disease Events, and an Expanded Model

Ten‐year atherosclerotic cardiovascular disease (ASCVD) risk prediction models include the pooled cohort equations (PCE) and the Predicting Risk of Cardiovascular Disease Events (PREVENT) models. We evaluated the relative contributions of predictors in these models, along with social determinants and emerging biomarker...

Yixin Zhang, Ernst J. Schaefer, Hiroaki Ikezaki et al. · Journal of the American Hear... · 0 citations