Therapeutic Potential of Berberine in Obesity-Associated Neuroinflammation Through Shared Molecular Pathways: TLR4/NF-κB/MAPK, ROS/NRF2 and NLRP3
Current evidence indicates that BBR modulates signaling pathways, reduces the production of pro-inflammatory cytokines, attenuates oxidative stress, and limits glial activation, and several studies suggest that BBR may help preserve the functional integrity of the blood–brain barrier and reduce neuronal damage associat...