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Aug 2026

Differential Modulation of Central Sensitization Pathways by Common Antipsychotics in a Paclitaxel-Induced Neuropathic Pain Model.

Neuropathic pain is a chronic condition characterized by central sensitization (CS) and inadequacy of current treatments. Although antipsychotics are considered potential adjuvant treatments, they are generally treated as a homogeneous class, and their specific anti-nociceptive mechanisms remain unclear. This study cha...

Ayşenur Budak Savaş, Fatma Yeşilyurt, C. Bayram et al. · 0 citations
Open access Sep 2026

Early Neuroprotective Effects of Erucic Acid and Gentisic Acid on Hippocampal Glutamate Concentrations and Alzheimer-like Molecular Alterations in an Intracerebroventricular Streptozotocin Rat Model

Background: Alterations in glutamatergic homeostasis have been implicated in Alzheimer’s disease, but the relationship between total hippocampal tissue glutamate and Alzheimer-like molecular alterations remains unclear. This study evaluated the early neuroprotective potential of gentisic acid (GA) and erucic acid (EA)...

Ibrahim Gecili, M. Ertuğrul, I. Okkay et al. · 0 citations

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