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Author

C. Broome

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Clinical trial Open access Oct 2026

Rilzabrutinib, an oral Bruton tyrosine kinase inhibitor, in patients with warm autoimmune haemolytic anaemia: a prospective, single-arm, multicentre, phase 2b safety and clinical activity study (LUMINA 2).

BACKGROUND Warm autoimmune haemolytic anaemia is a rare blood disorder characterised by haemolysis, anaemia, elevated thromboembolism risk, fatigue, and impaired quality of life. The selective Bruton tyrosine kinase inhibitor, rilzabrutinib, might increase haemoglobin through multi-immune modulatory mechanisms targetin...

Nichola Cooper, D. Kuter, H. Frederiksen et al. · 0 citations
Open access Oct 2026

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia.

Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4-year-old female with congenital tufting enteropathy, post-intestinal transplant patient on immunosuppressants, who devel...

Sarah Hsieh, Susmita N. Sarangi, Caileigh Pudela et al. · 0 citations

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