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C. Caldas

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Open access Aug 2026

Genomic subtypes inferred from clinical sequencing provide significant prognostic stratification in metastatic breast cancer

Purpose. The 11 Integrative Cluster (IntClust) genomic subtypes of breast cancer have both prognostic and predictive value but require integrated DNA copy-number and gene expression profiling, which are not routinely used in clinical care. We tested whether IntClust could be inferred from clinical DNA targeted gene pan...

A. Yaacov, A. Grinshpun, P. Pharoah et al. · 0 citations

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