Author

C. Calfee

2 papers indexed here

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Review Open access Sep 2026

Lung‐Cardiovascular Interactions and Derangements in ARDS

ABSTRACT The acute respiratory distress syndrome (ARDS) is fundamentally characterized by alveolar injury, leading to lung edema, severe hypoxemia, and poorly compliant lungs. Alveolar and cardiovascular pathology are deeply intertwined in the syndrome, which can be marked by clinical cardiac, pulmonary, and systemic v...

P. A. Sanchez, Connor G. O'Brien, M. Legrand et al. · Comprehensive Physiology · 0 citations

Open access Sep 2026

GDF15 as a biomarker of metabolic dysfunction and mortality in sepsis and ARDS: a cohort study

GDF15 is a biomarker of mitochondrial metabolic dysfunction and is prognostic across three trial populations of sepsis and ARDS, but it was not independently associated with mortality in a smaller observational cohort, and is a candidate for prognostic enrichment in trials of metabolically targeted therapies, though wh...

N. Alipanah-Lechner, Carolyn Leroux, A. Ringor et al. · Critical Care · 0 citations