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Open access Jul 2026

Emergence of Disease-relevant Aberrant Epithelial Cell States in Human Alveolar Organoids.

How primary human alveolar epithelial organoids respond to a commonly-used commercial alveolar differentiation media intended to facilitate AT2->AT1 differentiation (ADM) in isolation and following biased HIF activation is investigated to position HIF2 as a critical potentiator of aberrant alveolar epithelial cell stat...

H. David, A. Dietrich, C. Calvi et al. · 1 citation

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