Author

C. Carraro

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Open access Sep 2026

ConvexGating infers gating strategies from clusters in single cell cytometry data

Manual expert gating remains common practice for defining specific cell populations in flow cytometry data, but increasing numbers of measured parameters and high inter-rater variability limit consistency across studies. Cluster-based approaches use the full marker space to define cell populations more consistently, bu...

V. Friedrich, Karola Mai, T. Hofer et al. · Nature Communications · 0 citations

Open access Aug 2026

A reproducible three-dimensional model of human brain tissue to investigate physiological and disease-associated microglia phenotypes

A reproducible human three-dimensional brain tissue model with neurons, astrocytes and microglia, replicating in-vivo-like maturation and enabling the study of Alzheimer’s disease-relevant perturbations and drug responses is developed.

Julien Klimmt, Carolina Cardoso Gonçalves, J. V. Montgomery et al. · Nature Neuroscience · 1 citation