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C. Cecil

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Open access Sep 2026

826. Polygenic liability to psychiatric disorders predicts depressive and anxiety symptoms across pregnancy and postpartum

Abstract Background Pregnancy and the postpartum period constitute a high-risk window for the emergence of depressive symptoms. Peripartum depression (PPD) affects around 17% of women worldwide [1] and remains substantially underdetected, with clinically meaningful consequences for maternal functioning, mother-infant b...

B. Vai, L. Fortaner-Uyà, M. Shahisavandi et al. · 0 citations
Open access Aug 2026

DNA methylation signal of birthweight generalizes to high-risk pregnancies and is independent of genetic, maternal, and obstetric factors: a twin study

DNA methylation is associated with individual differences in birthweight in a high-risk clinical population of MC twins, independent of shared genetic, familial, maternal, and obstetric factors.

M. Sulaiman, L. Franken, J. A. Spekman et al. · 0 citations
Open access Aug 2026

Perinatal risk factors, DNA methylation and the development of ADHD symptoms: a high-dimensional mediation analysis

A role of DNAm at birth in mediating the association of maternal smoking, birth weight and ADHD-related genetic variants with ADHD symptoms is demonstrated, however, lack of individual site-specific findings and the observational design limit causal biological interpretations.

A. Neumann, M. Suderman, J. Felix et al. · 0 citations

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