C. Chiasson-MacKenzie

Merlin restoration prevents schwannoma progression in a genetically engineered mouse model of NF2 -SWN

Purpose Patients with NF2-related schwannomatosis (NF2-SWN) present with hallmark bilateral vestibular schwannomas, but also schwannomas on other cranial, spinal, and peripheral nerves, as well as meningiomas and ependymomas, caused by germline mutations in the tumor suppressor gene NF2. Current therapies involving sur...