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Open access Aug 2026

De novo design of RNA pseudoknots with deep learning.

It is shown that intricate RNA structures can be generated with current deep learning tools through accurate de novo design of pseudoknot secondary structures, suggesting that some difficult RNA design tasks may be tractable without first solving RNA 3D structure prediction.

J. Townley, W. Kladwang, David Baker et al. · 1 citation
Open access Jul 2026

ADAPT-M: a workflow for rapid, quantitative in vitro measurements of enriched protein libraries

Affinity Determination by Adaptation of ProTein binders for Microfluidics enables rapid, parallel measurement of binding affinities and dissociation behavior directly from enriched display libraries in under one week, without requiring gene synthesis or hands-on protein purification.

Carla P. Perez, N. DelRosso, Cameron L. Noland et al. · 0 citations

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