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C. Chute

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Open access Sep 2026

Increasing Multimorbidity Burden After COVID-19 Infection Among People With and Without HIV in the United States: Insights From the National Clinical Cohort Collaborative (N3C)

Abstract Background People with HIV (PWH) have a disproportionately high burden of chronic comorbidities. However, how their multimorbidity patterns differ from those of the general population and how COVID-19 infection may affect this burden have not been well characterized. Methods We conducted a retrospective cohort...

Yu-Meng Wang, Ahmed Sabit, J. Anzalone et al. · 0 citations
Open access Sep 2026

Standards Developer Organizations (SDOs) and the advancement of biomedical data utility: Recommendations for modifying or extending content

Abstract Scientific progress increasingly relies on large, complex biomedical datasets; data management concerns (heterogeneity, volume, sensitivity, and a pervasive lack of standardization) present significant challenges, especially in the context of AI adoption and precision medicine. This fragmented data landscape l...

C. Chute, A. Bahmani, Alex H. Wagner et al. · 0 citations
Open access Aug 2026

Real-world effectiveness of early nirmatrelvir/ritonavir initiation after COVID-19 diagnosis in outpatient setting against severe illness, hospitalization, death, and long COVID in N3C

Evaluated the real-world effectiveness of NMV-R in preventing severe illness, hospitalization, death and long-COVID in a large nationwide cohort of outpatients with COVID-19 and found it overall effective at preventing the risk of severe acute outcomes including hospitalization and death, as well as long COVID.

Steve R Makkar, Kristen Hansen, Arjun S. Yadaw et al. · 0 citations

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