Review
Open access
Aug 2026
Primary Mitochondrial-Disorders-Associated Nephropathy in Adulthood
Oxidative phosphorylation (OXPHOS) is the main source of cellular adenosine triphosphate (ATP) production and depends on proteins encoded by both mitochondrial and nuclear DNA (nDNA). Pathogenic variants affecting this dual genetic control cause primary mitochondrial disorders (MIDs), which follow either maternal inher...
Hugo Bakis, A. Trimouille, Maximilian Schwarz et al.
· Kidney International Reports · 0 citations