RATIONALE
Airway mucus plugs are a prognostic marker in moderate-to-very severe chronic obstructive pulmonary disease (COPD), but their association with respiratory outcomes has been insufficiently evaluated among participants with preserved spirometry and asymptomatic COPD.
OBJECTIVES
To investigate the association...
Fan Wu, Fan Wu, Ting-Ting Xia et al.· American Journal of Respirat...· 0 citations
BACKGROUND
Moderate-to-severe and severe respiratory exacerbations in chronic obstructive pulmonary disease (COPD) accelerate lung function decline. However, whether any mild-to-severe exacerbations are associated with lung function decline in COPD remains unclear, especially in mild-to-moderate COPD and in the Global...
K. Zhou, Fan Wu, Q. Wan et al.· Respiratory Medicine· 0 citations
Increased depressive symptoms were associated with a higher risk of pre-COPD phenotypes, respiratory symptoms, and mortality, and may be a treatable trait that can help mitigate adverse outcomes in participants with pre-COPD.