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Review Open access Oct 2026

Pancreatic β-cell mitogenic regeneration in type 1 diabetes: A preclinical review.

Type 1 diabetes (T1D) is caused by autoimmune destruction of insulin-producing pancreatic β-cells, resulting in hyperglycaemia. The first-line treatment for symptomatic T1D is exogenous insulin replacement to maintain glycaemic control. Islet transplant therapy is available to a small number of individuals, and stem ce...

J. Cantley, L. Logie, P. Narendran et al. · 0 citations

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