Author

C. De Angelis

2 papers indexed here

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Open access Aug 2026

Adipocyte-derived estrogen signaling influences TROP2 expression in ERα-positive breast cancer

Background Obesity-associated alterations in the tumor microenvironment (TME) modulate breast cancer (BC) progression. In obese individuals, adipocytes, the predominant stromal component of breast tissue, display an altered endocrine and inflammatory profile, leading to increased secretion of hormones, adipokines, and...

L. Gelsomino, Linda Manna, Vittoria Marchio et al. · Frontiers in Endocrinology · 0 citations

Review Open access Jul 2026

Unraveling the use of vaccine therapy in HER-2 positive breast cancer: a comprehensive review of current state and future perspectives

Despite significant advances in early detection and therapeutic strategies, breast cancer (BC) continues to pose a major public health challenge. The treatment of HER2-positive (HER2 +) BC has evolved substantially over recent years with the advent of monoclonal antibodies (mAbs), small-molecule tyrosine kinase...

A. Caltavituro, C. Martinelli, M. Palleschi et al. · Journal of Experimental &amp... · 0 citations