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C. Deleschaux

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Review Open access Sep 2026

Autophagy Defects and Mitochondrial Retention in Erythroid Diseases

Erythropoiesis requires extensive cellular remodeling, culminating in enucleation and organelle clearance to generate mature red blood cells (RBCs). Over the past 15 years, accumulating evidence has established that macroautophagy—particularly ULK1-, NIX-, and PINK1-dependent mitophagy—plays a central role in erythroid...

C. Fader, J. Jacob, Santiago Castro Perez et al. · 0 citations

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