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C. Frisbie

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Open access Sep 2026

A Novel SXXLF Motif in the FXR N‐Terminal Domain Mediates Coregulator and Interdomain Interactions

The nuclear receptor (NR) superfamily is comprised of ligand‐regulated transcription factors that contain an intrinsically disordered domain at the amino‐terminal end, known as the N‐terminal domain (NTD). While this poorly conserved domain is known to possess ligand‐independent activation function (AF‐1), few NTD func...

Priscilla Villalona, Thilini Pulahinge, Tracy Yu et al. · 0 citations

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