Author

C. Fuchsberger

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Open access Jul 2026

Beyond the classical plasma secretome: genetic architecture and disease associations of the expanded human plasma proteome in 13,445 Europeans

Circulating plasma proteins are key biomarkers and therapeutic targets, now measurable at scale through high-throughput technologies, yet whether expanding proteomics platforms beyond the classical plasma secretome enhances genetic discovery and causal inference remains poorly understood. Here, we use an expanded SomaS...

S. Cadiou, E. Konig, A. Mapelli et al. · medRxiv · 0 citations

Open access Jul 2026

Artificial intelligence-based ECG reconstruction error as a continuous predictor of all-cause mortality: a multi-cohort retrospective validation study

This work aimed to develop a self-supervised AI-ECG risk score based on the error in reconstructing a partially masked ECG, providing a direct measure of how much each recording deviates from normal cardiac electrical patterns.

A. Nicolson, S. ProÌll, R. Lunelli et al. · medRxiv · 0 citations