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Optimization of tick identification via MALDI-TOF MS for implementation in routine diagnostics
Ticks are important vectors of pathogens with substantial medical and veterinary relevance, a threat that may be further increased with the spread of invasive tick species. Reliable tick identification is relevant for accurate diagnostic elucidation of transmission pathways, and the development of targeted surveillance...
Genetic variation in HLA, IGKV, and HHEX loci influences mRNA vaccine-induced humoral protection against COVID-19.
Humoral immune responses to COVID-19 vaccination vary widely across individuals, yet the genetic determinants of functional antibody protection beyond binding antibodies after two immunizations remain poorly understood. We performed genome-wide association studies on antigen-specific antibody concentrations and live-vi...