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C. Gerardo

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Open access Sep 2026

Adjunctive Varespladib after antivenom administration for snakebite: A phase II randomized clinical trial

Background Snakebite envenoming causes an estimated 81,000–138,000 deaths and more than 400,000 cases of permanent disability each year, disproportionately affecting low-resource regions. Antivenom is the only approved treatment but requires intravenous administration. We evaluated intravenous followed by oral varespla...

C. Gerardo, Ashish Bhalla, Chittaranjan Mohanty et al. · 0 citations
Review Open access Sep 2026

Varespladib for snakebite envenoming: insights from therapeutic development and clinical trials

Clinical evidence from two clinical studies in patients with SBE supports further evaluation of varespladib as an in-hospital treatment administered, with encouraging signals from Agkistrodon contortrix (copperhead), Micrurus fulvius (eastern coral snake), and Bungarus spp (krait).

Madison McGann, T. Platts-Mills, C. Gerardo · 0 citations

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