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Open access 2026

Sophoraflavanone G decreases the migratory ability of cancer cells by altering the cytokine profile of the environment in endometrial cancer and macrophage co-culture

Background : Macrophages play key roles in initiating, sustaining, and resolving inflammation. Sophora flavescens has traditionally been used as a herbal anti-inflammatory treatment for inflammation-related conditions. This study aimed to investigate how sophoraflavanone G (SF-G) modulates the inflammatory response in...

F. Çelik, C. Gunes · 0 citations
Open access Sep 2026

Antidepressant potential of agmatine: Effects on hypothalamic neurogenesis in rats with depressive behavior.

This study aimed to investigate the behavioral, neuroendocrine, and hypothalamic molecular effects of agmatine in rats exposed to chronic mild stress (CMS). 28 adult male Wistar albino rats were randomly allocated to four groups: Control, CMS, CMS + Agmatine (CMS + A), and Agmatine (A) (n = 7/group). A repeated CMS sch...

H. Solak, C. Gunes, A. Küçük et al. · 0 citations

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