Open access
Aug 2026
CYP19A1 variation in healthy children: associations with breast development and pubertal gynecomastia
Background CYP19A1 encodes aromatase, the enzyme converting androgens to estrogens, thereby influencing breast tissue development in healthy children. Objective To examine associations between CYP19A1 single nucleotide polymorphisms (SNPs) and circulating estradiol (E2) and testosterone (T), the E2/T ratio and age at t...
Veronica L R Groendahl, S. Holmboe, A. Busch et al.
· Endocrine Connections · 0 citations