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C. Happle

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Open access Aug 2026

A Three-Year Practice-Based Mixed-Methods Feasibility Evaluation of a Community-Based Inclusive Physical Activity Program for Autistic Youth

Autistic children and adolescents often encounter social, sensory, and environmental barriers to participation in group-based physical activity. This study evaluated the feasibility, safety, and participation-related processes of a community-based inclusive physical activity program in Germany that used adapted rugby...

Torge Wittke, Marina Siebert, Maike Emmerich et al. · 0 citations
Open access Sep 2026

Host cell entry and neutralisation sensitivity of H3N2 influenza A virus subclade K

Using pseudovirus particles, it is shown that subclade K-HA drives augmented entry into certain cell lines and displays significant antibody evasion, suggesting that current vaccines may provide considerable protection.

Nicole Moor, N. Chen, G. Behrens et al. · 0 citations
Sep 2026

Circulating markers of organ damage associate with COPD in people with HIV: an exploratory proteomic analysis.

These findings provide exploratory evidence for candidate circulating organ damage markers of COPD in PWH and provide a basis for further studies into the mechanisms and immunopathology of this comorbidity, including studies in larger cohorts with HIV-negative comparator groups.

L. Riemann, Lena Böger, Carina Dahl et al. · 0 citations
Open access Jul 2026

Systemic inflammatory networks in HIV-associated chronic obstructive pulmonary disease.

PLWH with COPD exhibit distinct inflammatory signatures characterized by enhanced tissue damage, immune activation, and dysregulated repair mechanisms, providing insights into HIV-related COPD.

L. Riemann, Lena Böger, Carina Dahl et al. · 0 citations
Open access Jul 2026

Increased high sensitivity C-reactive protein in more severe wheeze/asthma phenotypes in child- and adulthood in ALLIANCE

HsCRP was increased in adult asthmatics compared to HCs and was associated with several severity-related clinical characteristics, whereas ICS use in preschool wheezers was associated with lower hsCRP levels.

Lena Lagally, Lena Ullemeyer, J. Omony et al. · 0 citations
Open access Jul 2026

JN.1-adapted vaccination is associated with readjustment of ancestral memory B cells toward neutralization within the JN.1 antigenic space

It is proposed that there is somatic hypermutation of existing B cell clones rather than de novo generation from naive B cells in JN.1-adapted booster vaccines and this finding indicates maturation of pre-existing, class-switched MBC rather than substantial de novo recruitment of naïve B cells.

M. Stankov, Matthias Bruhn, M. Hoffmann et al. · 0 citations

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