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Author

C. Hartmann

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Open access Sep 2026

Comparative Pharmacokinetics of Trientine Dihydrochloride Capsules: A Randomized, Open-Label, Reference-Controlled, Two-Period Crossover Study in Healthy Volunteers.

BACKGROUND AND OBJECTIVES Trientine dihydrochloride (TETA-2HCl) is an oral copper chelator used for Wilson disease. Because available formulations differ in marketed strength and may have formulation-specific pharmacokinetic properties, this study compared a 250 mg test capsule and a 300 mg reference capsule administer...

C. Hartmann, F. Tacke, I. Mohr et al. · 0 citations

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