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C. Hayes

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#small language model Open access Oct 2026

Atherosclerotic cardiovascular disease risk is associated with AT(N)V neuroimaging biomarkers and cognitive impairment in the health and aging brain study–health disparities cohort

Cardiovascular risk is increasingly recognized as relevant to cognitive aging and dementia-related brain changes, yet its relationship to multimodal neuroimaging biomarkers of amyloid, tau, neurodegeneration, and vascular injury (AT(N)-V) remains incompletely understood in racially and ethnically diverse cohorts. W...

K. Espejo, Ryan Rulkens, C. Hayes et al. · 0 citations
Open access Sep 2026

Plasma p-tau181 moderates the association between ten-year atherosclerotic cardiovascular disease risk and mild cognitive impairment – HABS-HD

Greater ten-year ASCVD risk was consistently associated with cognitive impairment independent of plasma AD biomarkers, with evidence that p-tau181 modifies these associations and that their magnitude varies across racial and ethnic groups.

J. Contreras, N. Ortega, Raymond Jones et al. · 0 citations
Open access Jun 2026

Interleukin-6 is Associated with White Matter Hyperintensities and Cognition Independent of Alzheimer’s Disease Plasma Biomarkers – HABS-HD

Elevated IL-6 is independently linked to cerebrovascular injury and poorer cognition beyond classical AD biomarkers, supporting a vascular–inflammatory pathway distinct from amyloid and tau pathology.

A. Dharmapuri, Soumilee Chaudhuri, J. Contreras et al. · 0 citations

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