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Open access Oct 2026

Germline pharmacogenetic variants associated with trastuzumab deruxtecan-induced interstitial lung disease in advanced breast cancer: PROCURE project

Background Trastuzumab deruxtecan (T-DXd) has demonstrated substantial clinical benefit in patients with advanced human epidermal growth factor receptor 2 (HER2)-positive and HER2-low breast cancer. However, treatment-related adverse events—particularly interstitial lung disease (ILD) or pneumonitis—represent a clinica...

A. Arenas, C. Saura, M. Alva Bianchi et al. · 0 citations

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